QP-Liver

MRI-based automated liver segmentation and accurate fat and iron quantification.

Improve the diagnosis of diffuse liver diseases through highly accurate quantification of tissue fat and iron from MRI. Quibim builds a new product that leverages the best AI models for highly accurate automated liver segmentation. The methodology has been validated against digital pathology.

References

  1. Martí-Aguado D, Jiménez-Pastor A, Alberich-Bayarri Á, Rodríguez-Ortega A, Alfaro-Cervello C, Mestre-Alagarda C, Bauza M, Gallén-Peris A, Valero-Pérez E, Ballester MP, Gimeno-Torres M, Pérez-Girbés A, Benlloch S, Pérez-Rojas J, Puglia V, Ferrández A, Aguilera V, Escudero-García D, Serra MA, Martí-Bonmatí L. Automated Whole-Liver MRI Segmentation to Assess Steatosis and Iron Quantification in Chronic Liver Disease. 2022 Feb;302(2):345-354. doi: 10.1148/radiol.2021211027. Epub 2021 Nov 16. PMID: 34783592. https://pubmed.ncbi.nlm.nih.gov/34783592/
  2. Jimenez-Pastor A, Alberich-Bayarri A, Lopez-Gonzalez R, Marti-Aguado D, França M, Bachmann RSM, Mazzucco J, Marti-Bonmati L. Precise whole liver automatic segmentation and quantification of PDFF and R2* on MR images. Eur Radiol. 2021 Oct;31(10):7876-7887. doi: 10.1007/s00330-021-07838-5. Epub 2021 Mar 25. PMID: 33768292. https://pubmed.ncbi.nlm.nih.gov/33768292/
  3. França M, Martí-Bonmatí L, Silva S, Oliveira C, Alberich Bayarri Á, Vilas Boas F, Pessegueiro-Miranda H, Porto G. Optimizing the management of hereditary haemochromatosis: the value of MRI R2* quantification to predict and monitor body iron stores. Br J Haematol. 2018 Nov;183(3):491-493. doi: 10.1111/bjh.14982. Epub 2017 Oct 30. PMID: 29082508. https://pubmed.ncbi.nlm.nih.gov/29082508/
  4. França M, Martí-Bonmatí L, Porto G, Silva S, Guimarães S, Alberich-Bayarri Á, Vizcaíno JR, Pessegueiro Miranda H. Tissue iron quantification in chronic liver diseases using MRI shows a relationship between iron accumulation in liver, spleen, and bone marrow. Clin Radiol. 2018 Feb;73(2):215.e1-215.e9. doi: 10.1016/j.crad.2017.07.022. Epub 2017 Aug 31. PMID: 28863932. https://pubmed.ncbi.nlm.nih.gov/28863932/
  5. França M, Alberich-Bayarri Á, Martí-Bonmatí L, Oliveira P, Costa FE, Porto G, Vizcaíno JR, Gonzalez JS, Ribeiro E, Oliveira J, Pessegueiro Miranda H. Accurate simultaneous quantification of liver steatosis and iron overload in diffuse liver diseases with MRI. Abdom Radiol (NY). 2017 May;42(5):1434-1443. doi: 10.1007/s00261-017-1048-0. PMID: 28110367. https://pubmed.ncbi.nlm.nih.gov/28110367/

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Interested on learning more about QP-Liver?

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