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QUIBIM’s AI-FUELED CHEST X-RAY CLASSIFIER GETS CE MARK

  • Chest X-ray classifier is added as a new CE cleared tool within QUIBIM Precision platform, which already received CE mark class IIa certification earlier in 2019.

  • QUIBIM’s Chest X-Ray Classification AI-Tool dynamically learns using new images, meaning the system is continuously evolving and improving over time.

Valencia, Spain – 27th May 2019. Spanish healthcare AI company QUIBIM today announced that its AI-powered Chest X-Ray Classification tool has received CE certification. The company already obtained the class IIa CE mark earlier this year for the imaging biomarker analysis algorithms, the zero footprint DICOM viewer and the platform within the QUIBIM Precision platform, becoming the first Spanish firm to ever receive the clearance.

QUIBIM applies machine learning and image processing techniques to extract imaging biomarkers from medical images in order to assist radiologists and physicians in daily practice. With its AI-based chest x-ray classifier, QUIBIM helps to detect pathological findings that could go unreported due to the heavy workload of radiology departments.

QuibimStructuredReport_Chest X Ray Classifier

“Our tool was designed to prioritize unreported, potentially pathological radiographs, to help radiologists be more efficient by focusing their efforts on studies that are more likely to have pathologies. We are sure this will have an impact in big healthcare systems,” Angel Alberich-Bayarri, QUIBIM CEO and founder, explained.

The solution makes use of a novel architecture based on referee networks combined with Convolutional Neural Networks that have been trained with a database of more than 500,000 images, to calculate the final probability of the X-Ray of being abnormal. Afterwards, the probabilities are used to estimate the presence of pathologies in chest X-Rays.

Because of this Artificial Intelligence methodology, the classifier understands the visual patterns that are most indicative of the different pathologies using the knowledge extracted from the large dataset of radiographs used to train the networks. “QUIBIM’s Chest X-Ray Classification Tool is able to learn further using new images, which means that this system is continually improving and evolving with time,” Rafael López, Artificial Intelligence Engineer at QUIBIM, said.

QUIBIM’S Chest X-Ray Analysis Tool is already available at QUIBIM Precision®, accessible through the cloud with just a few clicks or it can be fully integrated in the radiology department’s workflow as a local solution for seamless interpretation of chest X-Rays.

Welcome post QUIBIM - José Gascón and José Sánchez 2

Our family keeps growing

We are proud to announce the incorporation of two new Quibimers in our growing team. Both excellent computer scientists, passionate about practising sport and named José!

José María Gascón Artal

In our Development Department, we welcome José Gascón Artal as Full Stack Web Developer. With nearly 4 years of previous experience in the IT sector working in the multinational technology consultancy as a Software Developer and in Communications agencies as Chief Technology Officer, he has joined our development team to help keep developing and improving the QUIBIM Precision Platform with new features.

Thanks to his great knowledge of JavaScript technology and his agile way of working we are sure he will play an important role in future QUIBIM’s milestones.

José is enthusiastic about developing his own apps with the technology stack MEAN and when he is not with his PC you can find him riding his motorbike, snowboarding or playing volleyball.

José Sánchez García

With a Bachelor’s and Master’s Degree in Telecommunication Engineering, both at the Polytechnic University of Valencia (UPV), and a specialization in Deep learning and Computer Vision algorithms, José Sánchez García has become part of our team as Data Scientist in the AI (Artificial Intelligence) area. A part-time job he combines with the role of Biomedical Engineer at the Fundación Hospital Provincial de Castellón, where he is in charge of new imaging biomarkers development and its integrations into QUIBIM Precision Platform.

Previous to join QUIBIM José has worked in Visia Solutions, where he lead image processing projects in Ford and SRG Global between others and he was also Intern Programmer in Everis. It was during his Master’s Thesis that he started to collaborate with us integrating Artificial Intelligence in Neuroimaging Analysis and when the synergy arose.

To achieve comprehensive success, as he says, he likes to combine his time at work with working out at the gym, doing Crossfit and a healthy diet not to mention that José is also really keen on doing song covers and playing tennis.

We wish you both a brilliant future in QUIBIM. We couldn’t be happier to welcome you as a new Quibimers!

Meet our team

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QUIBIM at the annual Outsourcing in Clinical Trials Europe 2019

We are very happy to share with you QUIBIM´s experience at the last Outsourcing in Clinical Trials Europe 2019 from 14th to 15th of May in Milan (Italy).

Clinical Trials Manager and Chief Strategy Officer, Irene Mayorga and Kabir Mahajan, joined this annual meeting to introduce the services that QUIBIM offers to CRO’s and pharmaceutical companies conducting imaging clinical trials. They had the pleasure of interacting with many novel drug development companies & CRO’s focusing on glioblastoma, pancreatic cancer, other cancers and diffused liver disease and had the chance to show QUIBIM´s experience on this front.

Also, we had the opportunity to discuss QUIBIM´s services as an imaging core lab, not only with the scientific and technical aspects, but also with the design and development of imaging documentation such as the imaging trial charter, the medical imaging validation and imaging acquisition quality control,  statistical analysis and other standard clinical trials management services.

If you did not have the chance to join us in Milan, you can meet Irene Mayorga Ruiz and Kabir Mahajan at the BIO Convention in Philadelphia from June 3- June 6, 2019 where they would be showing the latest developments in the QUIBIM Precision platform for managing clinical trials. You can use the following link to book a demo.

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Breast cancer QUIBIM

QUIBIM uses AI to boost
breast cancer research

As the first ESMO Breast Cancer Congress unfolded 2-4 May in Berlin, Germany, QUIBIM CEO highlighted the role played by artificial intelligence (AI) in breast cancer research.

The European Society of Medical Oncology focused on the progress in treatment options and improved outcomes for breast cancer (BC) patients during its first meeting dedicated to the topic (¹).

One of the key messages of the conference was that therapeutic innovations should go hand in hand with a multidisciplinary, fully integrated approach to patient care, a scenario in which AI can increasingly help make a difference, according to QUIBIM CEO & founder Angel Alberich-Bayarri.

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QUIBIM breast cancer structured report

AI, and in particular image quantification, can help significantly advance knowledge of this multi-faceted disease, by enabling earlier and better detection,” he said.

From the Pacific to the rest of the world

Recently QUIBIM partnered with the AI Precision Health Institute (AI-PHI) at the University of Hawai‘i Cancer Center in Honolulu, to manage, store and quantitatively analyze medical images and algorithms in breast cancer research.

Using the QUIBIM Precision® image analysis platform, AI-PHI researchers will create large scale imaging repositories with automated extraction of imaging biomarkers to characterize patients’ status. The solution will first be used as the central repository for the mammography studies conducted in the Pacific and will include mammograms from over 5 million women.

The University of Hawai‘i Cancer Center is one of 69 NCI designated cancer centers in the United States and the only one in Hawai‘i and all of the Pacific Islands. It is the only institution that uses AI to analyze medical images to assess health and predict risk of disease in the region.

The project is expected to grow exponentially as its principal investigator Dr. John Shepherd is keen on inviting selected reference centers all across the world to join the network. “It is a very interesting and pioneering work for QUIBIM, and our first big cooperation in the breast cancer setting,” Alberich said.

Seamless integration into clinical workflow

The QUIBIM Precision® image analysis platform enables to incorporate AI algorithms regardless of the institution where it is deployed, to facilitate integration into workflow.

“Researchers can program their own algorithm and code, and add it as a plugin to the platform. This feature, combined with the advanced storage and multi-user annotation capabilities of the platform, allows for a wide adoption within research groups and institutions working with AI. Time for deployment of algorithms in the real world is shortened by 25%, since you have the whole AI pipeline in just one place,” he explained.

The solution, which includes not only quantitative image analysis but also structured reporting capabilities, can be integrated into the radiology workflow and add value to this service. It can for instance be used to integrate AI algorithms to detect cancer without the need of radiologists in a first-read.

Earlier this year the platform received CE Mark certification as class IIa Medical Device, including the imaging biomarker analysis algorithms, the zero footprint DICOM viewer and the platform hosting these components and medical imaging data. The platform is now available for commercial deployment in European hospitals and diagnostic imaging centers.

In addition to the platform, the certification includes 15 algorithms in the five key areas of interest of the company: oncology, neurology, musculoskeletal, liver and lung

Also included in the CE Mark certification is the DataMiner, which was designed in collaboration with the team of Prof. Daniel Keim from Konstanz University to provide advanced visual analytics of large databases of patients for population health management and scientific exploitation. The DICOM web viewer that enables the user to visualize the images of a sequence, draw ROIs or apply filters is also included in the certification.

QUIBIM applies machine learning to develop tools for imaging data quantification, to accelerate image reconstruction, segmentation, detection and data mining. Beyond the breast, the company has created AI algorithms to help detect changes produced by brain and prostate cancer, but also other diseases in the hematological scenario such as non-Hodgkin’s Lymphoma.

(¹): https://www.esmo.org/Conferences/ESMO-Breast-Cancer-2019?utm_campaign=PRESS%20-%20Breast&utm_source=hs_email&utm_medium=email&utm_content=72075686&_hsenc=p2ANqtz-9pH5mSHFhwzXnTGp6oSizohrD75uXccBxo1woBVGUFhJl3K5y_p4Ms4Hoa3LcwRJ_KvILSmOWhsrZxTZSWLwumEXOnOw&_hsmi=72075686

QUIBIM team

La biotecnológica Quibim asume la gestión del banco de imágenes médicas del Pacífico e Italia

  • La empresa participada por Angels, la sociedad de inversión de Juan Roig, cierra un convenio para formar a 5.000 radiólogos tras adaptar su plataforma de extracción de biomarcadores Quibim Precision como herramienta educativa

  • La empresa, que abre nueva sede en Valencia, permite ahorrar tiempo y dinero al sector de los ensayos clínicos gracias a su sistema de cuantificar parámetros en radiología y medicina nuclear

València, 18 de abril de 2019.- La biotecnológica valenciana Quibim ha asumido la gestión del biobanco de imágenes médicas del Pacífico, tras cerrar un acuerdo con el centro de investigación del cáncer de la Universidad de Hawaii. La startup, participada por la sociedad de inversión de Juan Roig Angels, acaba de convertirse, además, en proveedor de este mismo servicio para imágenes médicas en Italia, gracias al sistema Quibim Precision, una plataforma de algoritmos de inteligencia artificial y análisis de imágenes radiológicas que fue desarrollado por esta joven empresa (fundada en 2012) con financiación del programa H2020 de la Comisión Europea.

El sistema Quibim Precision permite analizar imágenes médicas en la nube -aunque puede instalarse en versiones locales en hospitales o compañías- a partir de pruebas de rayos X, ecografías, TAC, resonancias magnéticas (RNM) o PET. Gracias a la aplicación de algoritmos de análisis, el software de Quibim posibilita extraer datos cuantitativos, que sirven para que el profesional médico haga el diagnóstico con más información.

Estos parámetros extraídos reciben el nombre de Biomarcadores de Imagen y aportan datos extraídos de imágenes médicas, relacionadas con procesos biológicos normales, enfermedades (por ejemplo tumores) o respuestas terapéuticas. Los modelos computacionales aplicados a las imágenes sirven para medir de manera objetiva los cambios producidos por una lesión o por tratamientos farmacológicos.

La tecnología Quibim se aplica en la práctica clínica, los ensayos clínicos, la formación en radiología y los proyectos de investigación. Con la adaptación de la plataforma al sector de la investigación se puede hacer una evaluación más temprana sobre la respuesta a los tratamientos en ensayos clínicos, con el consiguiente ahorro de tiempo y dinero, aspectos clave en cualquier proyecto de I+D+i.

Quibim ha cerrado un acuerdo con la Escuela Europea de Radiología (European School of Radiology, ESOR) para que su plataforma de apoyo al diagnóstico sirva como herramienta de formación para más de 5.000 radiólogos en todo el mundo. Ello gracias a que la plataforma ha sido adaptada como instrumento educativo. Actualmente, los radiólogos han de recurrir a meras imágenes proyectadas en power point en sus procesos formativos. La joven startup está inmersa en un proceso de expansión internacional. Hoy está ya presente en España, Reino Unido, Italia, Holanda, Dinamarca, Polonia, Portugal, Chile, Uruguay, Argentina, Estados Unidos, Taiwán, Japón e India.

Entre sus objetivos en este 2019, tras conseguir el marcado CE el pasado año, está conseguir la certificación FDA -un prestigioso sello médico para comercializar en Estados Unidos-  para consolidar una fuerte presencia en este país, ampliar la cobertura  a 60 hospitales y centros de diagnóstico y participar en una docena de nuevos ensayos clínicos de ámbito nacional e internacional.

Inaugura sede corporativa en Valencia

Quibim acaba de inaugurar nueva sede corporativa en Valencia, en el Edificio  Europa, uno de los hubs de negocio de la ciudad. La compañía biotecnológica ha crecido en los últimos cinco años hasta convertirse en una de las siete pymes que lidera mundialmente el desarrollo de tecnologías de postprocesado de imágenes médicas basadas en inteligencia artificial. Cuenta también con oficinas en Madrid y Palo Alto (California). En la compañía trabajan ya una veintena de profesionales.

Según Ángel Alberich-Bayarri, CEO y fundador de la compañía, “estas nuevas instalaciones representan un paso más para la compañía. Comenzamos de forma activa en 2014 con una idea dentro del programa Lanzadera y hoy celebramos con la inauguración de nuestra nueva oficina la evolución que ha tenido la empresa a lo largo de estos años, un gran hito para QUIBIM”.

Sobre Angels

Angels es la sociedad de inversión impulsada por el empresario Juan Roig que tiene como objetivo invertir en líderes emprendedores para desarrollar empresas sostenibles. Ofrece un modelo de gestión basado en el Modelo de Calidad Total, su red de contactos, así como toda la infraestructura necesaria para acompañar al emprendedor, comenzando por las oficinas situadas en el entorno del polo emprendedor Marina de Empresas.

Sobre TechTransfer UPV

Tech Transfer UPV es el primer fondo de transferencia de tecnología impulsado dentro del sistema universitario español que apuesta por proyectos de transferencia de tecnología y emprendimiento generados en la Universitat Politècnica de València para acompañarlos en su salida al mercado.

Dispone de un patrimonio de 3,9 millones de euros. El Fondo está participado por 28 empresarios y profesionales valencianos y de Castellón de diferentes sectores que, además de invertir, participan como validadores de los proyectos. Entre ellos, el Instituto Valenciano de Finanzas, Caixa Popular Productos Citrosol, Air Nostrum, Grupo IVI, Multiscan, ACAL, Arca Telecom, S2 Grupo, Miarco, La Unión Alcoyana Seguros, Nero Family, Blast of partners, Tecnopaking, Vik Consultoría o Ca&CCA ingeniería.

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QUIBIM opens a
new office in Madrid

QUIBIM is proud to announce a new office in Madrid! This will enable us to better serve our national and international customers.

After the opening of a new office in the United States last year (Palo Alto, California), QUIBIM is continuing to grow and therefore the new office in the Spanish capital is an important milestone for QUIBIM. The office is located in Calle Alfonso XII, 62, next to the Atocha Train station of Madrid, and gives direct access to high-speed trains to Barcelona or Valencia. The office is present in the Spaces Atocha building, one of the Top Coworking Spaces in Madrid, which is within a 15 minute walk from various museums and gives a great atmosphere of innovation and technology just like the world’s great technology hubs like Berlin or Tel Aviv!

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Irene Mayorga, Clinical Trial Manager at QUIBIM, is the first permanent worker at the new office and It will grow as QUIBIM continues to expand.

QUIBIM trials department aims to help sponsors, CROs and investigators with radiological imaging in clinical trials and research projects. In this department we manage multi-site clinical trials in which we are involved as imaging vendor, providing services like:

  • Imaging charter creation and related documentation.
  • Image acquisition protocol design and consultancy.
  • QUIBIM Precision® platform configuration and setting up, allowing the centralization of medical imaging from different sites thanks to its web-based technology. The platform complies with CFR 21 part 11 from FDA and with the European data protection laws.
  • Training to imaging sites: protocol acquisition and image transmission through QUIBIM Precision® platform.
  • Site survey and site registration in the platform.
  • Validation of imaging sites using phantoms, to ensure that the data extracted from images acquired in different scanners are analogous therefore the conclusions extracted will be reliable.
  • Central radiological reading and imaging biomarkers quantification to reduce the inter-radiologist biases. This centralized approach is recommended by FDA in its 2018 guidance for “Clinical Trial Imaging Endpoints Process Standards”.
  • Sites follow-up and queries management.
  • Project management: meetings with sponsors, CRO or sites to ensure the correct execution of the trial.
  • Advanced statistical analysis on imaging biomarkers.

Feel free to visit us next time you are in Madrid!

QUIBIM TEAM ECR 2019

ECR 2019 sets the trend in Artificial Intelligence

The city of Vienna was at the real core of Medical Imaging and AI at the 25th European Congress of Radiology (ECR). At QUIBIM we always enjoy being at this annual meeting because it is the perfect combination of a science and industry exhibition. In this edition, the congress reached the milestone of 30,000 attendees, and the numbers are expected to go up with each year.

QUIBIM was glad to be participating in both, the scientific and industry sessions. Our oral presentations were mainly addressing current challenges of artificial intelligence (AI) and convolutional neural networks (CNN) in clinical needs like metabolic disorder, prostate cancer and osteoarthritis. Ana Jiménez-Pastor, Rafael López-González and Fabio García-Castro, R&D Engineers at QUIBIM presented our new research in image processing pipelines aiming to perform a virtual dissection of the organs through an automated segmentation combined with features extraction.

Personally,  I was happy to give 3 lectures focused on the future of radiology: 3D Post-processing in 2019, Deep Learning in Medical Imaging and Start-up in Radiology. In the 3D Post-processing lecture I introduced, what I think is the main revolution of AI in our field the concept of Virtual In-Vivo Dissection (VIVID), a name coined by my team and I at QUIBIM, which is a strategy of isolating human body organs in medical images for  characterization through features such as imaging biomarkers. This has several applications, challenges and is difficult to solve by traditional computer vision algorithms like liver or cartilage segmentation in Magnetic Resonance Imaging but it has become a reality thanks to the use of CNN architectures such as U-Net combined with deep supervision. In the Deep Learning in Medical Imaging session, I  focused on using other presentation formats and I was glad to give a TED talk and share the podium with Dr. Wiro Niessen, who spoke about Machine Learning in a Pecha Kucha format. This session was organized by the European School of Radiology (ESOR) and was chaired by Prof. Dr. Valérie Vilgrain, and I must say the atmosphere was excellent and the room was really packed! Finally, in a session chaired by Prof. Dr. Elmar Kotter,  we shared our insights on how to create a start-up company in Radiology from scratch, how to get funding from investors and the main considerations when scaling-up.

QUIBIM was also invited by the ECR to give a presentation within the Artificial Intelligence Exhibition (AIX) sessions, a new space for innovative AI companies. During this session, moderated by Dr Hugh Harvey and Dr Wim Van Hecke, we presented the newest version of the QUIBIM Precision V3.0 platform launched at the last RSNA 2018.

Welcome Mar Roca_QUIBIM

Mar Roca Sogorb joins QUIBIM as R&D projects Director

QUIBIM is growing rapidly! We are happy to announce the newest addition to our team. Mar Roca Sogorb has joined our company as Research and Development projects director. Due to her experience and background, she will help the research and innovation department with the upcoming projects and developments.

Mar received her formal training and defended her PhD thesis in astrophysics, but she decided to apply her knowledge in physics and in image processing tools to medical imaging.

Since then, she has been working on a large variety of topics related to magnetic resonance imaging (MRI) and spectroscopy (MRS). Mar has also developed dedicated algorithms for medical image denoising, segmentation and quantification for its integration into radiology workflow.

After a few years living in France, where she has been working as Research & Innovation Engineer at Olea Medical, Mar comes back to Valencia to join QUIBIM to support new algorithms development at the R&D department.

Congratulations! We officially welcome her and hope she has a prosperous career in the company.

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Meet us at ECR 2019

We are delighted to share that QUIBIM will attend the 25th European Congress of Radiology 2019 (ECR) from Wednesday, February 27th to Sunday, March 3rd, 2019. This year we have changed our standard location, now you can meet us at the AI Exhibition area (EXPO X1) booth #AI-15.

ECR attendees will have the opportunity to explore our latest version of the platform QUIBIM Precision® V3.0, focused on the Symbiosis of Radiology and Artificial Intelligence to seamlessly integrate imaging biomarkers into radiology workflows. Come and try our AI solutions and imaging biomarkers analysis!

Book a DEMO

Make sure not to miss our scientific contributions:

  • Wednesday, February 27:
    • 3D post-processing in 2019 – Dr. Ángel Alberich Bayarri.   |  Imaging Informatics, Artificial Intelligence and Machine Learning (Room N) – 16:00 – 17:30
    • Deeply supervised networks for the automated liver segmentation and quantification on MECSE-MRI – Ana Jiménez Pastor | EPOS
    • Stress testing a deep learning algorithm for normal/abnormal classification of Chest X-rays on a spectrum-biased abnormal – Rafael López Gónzalez  |  EPOS
      weighted dataset.
  • Thursday, February 28:
    • Functional imaging of the liver Chairperson’s introduction – Dr. Luis Martí Bonmatí. |  Abdominal Viscera, Contrast Media (Room M 5) – 10:30 – 12:00
    • AI PITCH – Dr. Ángel Alberich Bayarri.  |  Artificial Intelligence Exhibition (AIX) Theatre ( AIX Theatre) – 11:40
    • What to think about when writing a paper – Dr. Luis Martí Bonmatí. |  Education, General Radiology, Professional Issues (Room: C&T 3) – 14:00 – 15:00
    • Deep learning (DL) in medical imaging – Dr. Ángel Alberich Bayarri.   |  Education, General Radiology, Artificial Intelligence and Machine Learning (Room: M3) – 14:00 – 15:30
    • Quantification and evaluation of pre-post exercise femoral cartilage thickness and T2 changes in ultramarathon athletes – Fabio García Castro  |  Musculoskeletal, Imaging Methods (Room: O) – 14:00 – 15:30
    • How to manage critical reviews – Dr. Luis Martí Bonmatí. |  Education, General Radiology, Professional Issues (Room C&T 3) – 15:00 – 16:00
  • Friday, March 1:
    • ECR Academies: Radiology Leaders’ Bootcamp: Dream team Chairperson’s introduction –Dr. Luis Martí Bonmatí. |  Management/Leadership (Room M 2) – 10:30 – 12:00
    • Start-up in radiology – Dr. Ángel Alberich Bayarri.   |  Management/Leadership (Room M2) –  14:00 – 15:30
  • Saturday, March 2:
    • Automated Prostate multiregional segmentation in Magnetic Resonance using deeply supervised Convolutional Neural Networks – Rafael López González  |  Artificial Intelligence and Machine Learning, Oncologic Imaging, Imaging Informatics, Genitourinary, Physics in Medical Imaging (Room G) – 16:00 – 17:30
  • Sunday, March 3:
    • Automatic visceral fat characterization on CT scans through Deep Learning and CNN for the assessment of metabolic syndrome –  Ana Jiménez Pastor | Artificial Intelligence and Machine Learning, Abdominal Viscera, GI Tract, Oncologic Imaging, Imaging Informatics (Room D) – 14:00 – 15:30
    • Liver Case-Based Diagnosis Training – Dr. Luis Martí Bonmatí. |  Education, General Radiology, General Radiography (Radiographers) (Room E1) – 13:00 – 15:30

Join us at ECR 2019!

 For more information, get in touch with us at contact@quibim.com

Welcome Silvia Soler QUIBIM

New incorporation to QUIBIM Team!

We are happy to introduce you Mrs. Silvia Soler, who just joined the QUIBIM team as Executive Assistant & Team Coordinator.

Silvia has a degree in advertising and public relations by the University Rovira i Virgili (Tarragona) and a Master in Marketing and Sales Management by EFEM (Escuela de Formación Empresarial de Madrid). Her academic background provides a new perspective to QUIBIM and it will surely bring a wealth of knowledge and expertise in the fields of administration, management and communication.

Silvia has worked for many years as Administrative Assistant in one of the biggest Spanish hospital groups, so she is already familiarized with the healthcare environment. In QUIBIM, she will work closely to the Direction Department and will enhance the team coordination.

Beyond her professional side, Silvia likes running, going to the theater and hanging out with her friends. Her biggest passion is to travel around the globe and get to know other cultures. She will definitely become a Quibimer!

Congratulations! We officially welcome her and hope she has a prosperous career in the company.