
ABOUT
WHAT IS AN IMAGING BIOMARKER?
An imaging biomarker is a parameter obtained objectively from medical images, which represents and quantifies a tissue property (structural, functional or biological), extracted after applying computational models and signal processing to images in the space and time domains.
QUIBIM offers a head to toe imaging biomarkers solution. The development of each imaging biomarker involves a controlled step-by-step process, implemented by QUIBIM and adopted in 2013 by the European Society of Radiology (ESR) guidelines, to ensure accurate and consistent high quality measures.
We provide a comprehensive range of imaging biomarkers to professionals who want to distinguish themselves by choosing to offer an added value to diagnostic radiology, research and clinical trials:

Brain

Disease:
- Neurodegenerative (Amyotrophic Lateral Sclerosis, Parkinson, Alzheimer)
- Multiple Sclerosis
- Stroke
- Psychiatric disorders
- Traumatic Brain Injury
Biomarkers:
- Gray matter volumetry
- Cortical thickness
- Lesions segmentation
- Tractography
- Myelin mapping
- Iron concentration
- CSF dynamics
- Functional MRI
- Quantitative PET
Modalities:
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)

Musculoskeletal

Disease:
- Osteoporosis
- Oncology
Biomarkers:
- Morphometry analysis (trabecular thickness, trabecular spacing, trabecular number, 2D and 3D fractal dimension)
- Mechanical analysis (mechanical resistance and elasticity)
- Bone quality score
Modalities:
- Magnetic Resonance Imaging (MRI)
- Computed Tomography (CT)
- Micro-Computed Tomography (μCT)

Oncology and Hematology

Disease:
- Solid tumors: breast, prostate, rectum, lung, liver, brain, msk.
- Multiple myeloma
- Aggressive lymphoma
Biomarkers:
- Cellularity – Diffusion (ADC, IVIM, DKI)
- Angiogenesis – Pharmacokinetics
- Oxygen mapping
- Lesion burden
- Tumor textures
- Bone Marrow Infiltration
- Multi-Parametric Analysis
Modalities:
- Magnetic Resonance Imaging (MRI)
- Computed Tomography (CT)
- Positron Emission Tomography (PET)

Liver

Disease:
- Steatohepatitis
- Hemochromatosis
- Fibrosis
Biomarkers:
- Fat fraction
- Iron concentration
- Inflammatory activity
- Diffusion
- Textures
Modalities:
- Magnetic Resonance Imaging (MRI)
- Computed Tomography (CT)

Lung

Disease:
- Emphysema
- Chronic Obstructive Pulmonary Disease (COPD)
- Fibrosis
- Pulmonary hypertension
Biomarkers:
- Lung parenchyma volume
- Emphysema volume & distribution
- Lobe volumes
- Fractal dimension
- Airway stenosis
Modalities:
- Computed Tomography (CT)