Quibim | Liver fat and iron concentration

Biomarker / Abdomen / Liver fat and iron concentration

Description

Quibim has developed a virtual liver biopsy app that runs a fully automatic analysis of abdominal MR examinations containing a multi-echo chemical shift (MECSE) sequence with the help of AI.

The solution provides a simultaneous quantification of fat and iron concentration with a single-peak approach. The output of the app includes the parametric maps of fat and iron with voxelwise resolution and a quantitative structured report comparing the liver values of these imaging biomarkers to normative data.

This tool is useful for the early detection, diagnosis, treatment response evaluation and follow-up of a wide range of liver diseases.

Diseases

Diffuse liver diseases
Steatohepatitis
Hemochromatosis
Metabolic syndrome
Obesity
Fibrosis
Cirrhosis
Inflammation

References

França, M., Martí-Bonmatí, L., Porto, G., Silva, S., Guimaräes, S. and Alberich-Bayarri, Á. (2017). Tissue iron quantification in chronic liver diseases using MRI shows a relationship between iron accumulation in liver, spleen, and bone marrow. Clinical Radiology.

França, M., Alberich-Bayarri, Á. and Martí-Bonmatí, L. (2017). Accurate simultaneous quantification of liver steatosis and iron overload in diffuse liver diseases with MRI. Abdominal Radiology, 42(5), pp. 1434-1443.

Martí-Bonmatí, L., Alberich-Bayarri, Á. and Sánchez-González, J. (2012). Overload hepatitides: quanti-qualitative analysis. Abdom. Imaging. 37(2): 180-7.

Erturk, SM., Alberich-Bayarri, Á., Herrmann, KA., Martí-Bonmatí, L. and Ros, PR. (2009). Use of 3.0-T MR imaging for evaluation of the abdomen. Radiographics. 29(6): 1547-63.

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