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Dynamic Contrast Enhanced (DCE) PKM perfusion

Abdomen
Biomarker / Abdomen / Dynamic Contrast Enhanced (DCE) PKM perfusion

Description

Quibim has developed an app to automatically extract vascular-based imaging biomarkers to detect changes associated with increased tumor neoangiogenesis activity and aggressiveness.

The Pharmacokinetic (PKM) model used in the app helps detect neoplasms and quantifies tumor neoangiogenesis to stage cancer aggressiveness.

This tool is useful for the characterization of tumoral processes in the early detection, diagnosis, treatment response evaluation and follow-up of patients with cancer.

Diseases

  • Solid tumors
  • Prostate cancer
  • Rectal cancer
  • Endometrial cancer
  • Liver cancer

References

Martí-Bonmatí L, Ramírez-Fuentes C, Alberich-Bayarri Á, Ruiz-Llorca C. State-of-the-art of bone marrow imaging in multiple myeloma. Curr Opin Oncol. 2015 Nov; 27(6): 540-50.

Sanz-Requena R, Prats-Montalbán JM, Martí-Bonmatí L, Alberich-Bayarri Á, García-Martí G, Pérez R, Ferrer A. Automatic individual arterial input functions calculated from PCA outperform manual and population-averaged approaches for the pharmacokinetic modeling of DCE-MR images. J Magn Reson Imaging. 2015 Aug; 42(2): 477-87.

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